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Nose-To-Mouth Wrinkle Treatment with UV Chromophores
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Nose-To-Mouth Wrinkle Treatment with UV Chromophores

$72.00

(19 customer reviews) 
Cream 0.5 oz.

Beauty Award Winner – Elite Magazine’s Best Targeted Anti-Aging Brand

  • GIVE THE PROCEDURES A PASS: Reduce fine lines & wrinkles around the nose-to-mouth area (including those dreaded “marionette lines”) and help lift the jowl area the HYPER-NATURAL™ way.
  • STRUCTURAL REGENERATING: Formulated to stimulate the production of the structural proteins collagen, elastin & fibronectin in the deep layers of the skin.
  • SELF-HEALING: Normalizes cellular metabolism to reestablish intra- & extracellular communication – encouraging the skin to self-regenerate and ‘self-heal.’
  • LONG LASTING IMPROVEMENT: Experience on-going results and dramatic improvements with continued used.
  • SUN PROTECTION: UV chromophores strengthen the skin barrier function to protect itself from sun damage.

 

Amazon

The BIONOVA Nose-to-Mouth Wrinkle Treatment Cream with UV Chromophores is a very efficient and effective anti-aging and wrinkle treatment with stimulating and stunning results. Our product supports cell renewal that is helpful to recover damage. The treatment helps retain the firmness of the skin, refine the tone of the skin, reduce the appearance of wrinkles and fine lines of the skin, and also boost your skin’s brightness and radiance.

Modern life science industries’ approach to skin dysfunction is based on usage of a singular active substance (therapeutic agent) in high concentrations, often exceeding the maximum amount of biologically active substances naturally produced in a living system by thousands of times. The dosage and usage of a singular substance creates a new pathway that is foreign to the human organism and, in long term usage, may create multiple side effects of varying degree.

BIONOVA looks to the human body as one unified system regardless to where the “isolated problem” is occurring. It is all connected and belongs to the same individual physiological and biochemical system. BIONOVA’s technological platform allows for multiple substances to work synergistically in very low concentrations. This concept enhances the self-healing abilities and adaptation mechanisms of the cell without creating new damaging pathways. It is the most natural approach to skin dysfunction and reduces the amount of possible side effects as well as their severity.

Our proprietary skincare technology is based on NANO-COMPLEXES , compositions of 80-100 bioactive substances. NANO-COMPLEXES allow to target specific skin problems like Acne, dehydration or aging. NANO-COMPLEXES contain minute quantities of substances in nano and pico amounts, mimicking the quantities found in living organism. These amounts are sufficient to give dysfunctional cells what they need in order to restore normal inter- and intra-cellular communication, thus enhancing the skin’s own self-healing capabilities.

Key Ingredients:

Pro-Vitamin B5 (panthenol), vitamin B3 (niacinamide), vitamin E, short-chain polypeptides, lysine and other essential amino and nucleic acids, glycoproteins, hyaluronic acid, and other bioactive nutrient rich compounds

CREAM BASES:
Water (Aqua) / PEG 8 / Cetyl Dimethicone / Dimethicone / Cetyl Alcohol / Cetearyl Alcohol / Polysorbate 60 / PEG-150 Stearate / Steareth-20 / Polysorbate 20 / Glyceryl Stearate / Fragrance (Parfum) / Sodium Benzoate / Potassium Sorbate / Dehydroacetic Acid Sodium Salt / 2-Phenoxyethanol / Benzethonium Chloride / Sodium Sulfite / Imidazolydinyl Urea / Potassium Sorbate / Titanium Dioxide / Disodium Laureth Sulfosuccinate / Decyl Glucoside / Ammonium Sulfate / Sodium Benzoate / Potassium Chloride / Butyphenyl Methylpropional / Hydroxyisohexyl 3-Cyclohexine Carboxaldehide / Sodium Metabisulfite
NANO-COMPLEXES:
Hydroxypropyl-Cyclodextrin / Cholesterol / cis-9-Octadecanoic Acid / Hydrogenated Phosphatidylcholine / Bisabolol / Protein Stabilizers / Trehalose / Hydrolyzed Elastin / Sodium Chondroitin A / Phosphatidylcholine / Gluconolactone / Galactose / D-Glucose / Panthenol / cis-9,12 Octadecadienoic Acid / 1,2-Dihydro-3,6-pyridazinedione / Dodecanoic Acid / Tetradecanoic Acid / Galacturonic Acid / Calcium d-Gluconate / Hydrolyzed Collagen / Sodium Hyaluronate / cis-9,12,15-Octadecatrienoic Acid / Hexadecanoic Acid / Glutathione / Lactose / Fructose / Beta-Sitosterol / Ascorbic Acid / Maltose / Octadecanoic Acid / Docosanoic Acid / d-Mannose / Cholesteryl Acetate / Phosphatidylethanolamine / a-Ketoglutaric Acid / Proline / Centrophenoxine Hydrochloride / Glycine / Ergosterol / 1,2,3-Trioctadecanoylglycerol / Pantotenic Acid / Acetyl Cysteine / Cholic Acid Sodium Salt / Carnosine / Adenosin-Triphosphate / Niacinamide / Methyl Oleate / cis-9-Triolein / Adenine / Thymine / Uracil / Alanin / Cystein HCl / Lysine*HCl / Disodium EDTA / Gly-Gly-Gly / Hydroxyproline / Tocopheryl / Methyl Palmitate / Lipase / Nicotinamide Adenine Dinucleotide / Taurocholic Acid / Valine / Superoxide Dismutase / Ethyl Stearate / Acetyl Tyrosine / Taurine / Acetyl Carnitine HCl / Cytosine / Guanine / Tryptophan / Eicosanoic Acid / Dithiothreitol / Phenylalanine / Cupric Acetate / Indolacetic Acid / Stigmasterol / 1,2-Dimyristoyl-sn-glycero-3-phosphtidylcholine / 1,2-Distearoyl-sn-glycero-3-phosphatidylcholine / Retinyl Palmitate / Kinetin / 1,2-Dimyristoyl-sn-glycero-3-phosphtidylglycerol, Na / Xanthine / 1,2- Distearoyl-sn-glycero-3-phosphoethanolamine / 1,2-Dipalmitoyl-sn-glycero-3-phosphatidylglycerol, Na / 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine / Nonadecylic Acid / Thiamine Diphosphate / Adenosine / Genistein / Thioctic Acid / Ubiquinone / Phosphate Buffer / Adenosine Cyclic Phosphate / Gly-His-Lys / Thiamine Hydrochloride / Resveratrol / Uridine / Gly-Gly-His / Gly-Gly-Val / Pyridoxal-5-Phosphate / Arachidic Acid Methyl Ester / Sodium Molybdate / Morin / Val-Pro / b-Nicotinamide Adenine Dinucleotide Phosphate / Cytidine / Guanosine / Thymidine / Gly-Pro-Ala / Gly-Pro-Gly / Riboflavin 5-monophosphate Sodium Salt / Catechine / Folic Acid / Ala-Ala-Lys / Sodium Guanosine Cyclic Monophosphate / Tetracosonoic Acid / cis-6,9,12-Octadecatrienoic Acid / Guanosine-Triphosphate Sodium Salt / Astaxanthin / Collagen / Biotin / Quercetin / Rutin / Poly-L-Lysine Hydrobromide / apo-Transferrin / 1,2,3-Trieicosanoylglycerol / Coenzyme A / Carcinine / Tetrahydrofolic Acid / Arg-Gly-Asp / Tyr-Ile-Gly-Ser-Arg / b-Glucosidase / Sulfatase / Glucose Oxidase

Apply a small amount to clean dry skin prior to using other treatments. Pat gently in upwards motions onto the entire targeted treatment area from "jowl" area to nose, following the laugh lines. Relax facial muscles for approximately five minutes to facilitate product penetration

For best results, avoid layering other products directly over the immediate treatment area in order to allow the ingredients to engage directly with the skin cells (feel free to continue your regular routine on the other areas of your face).

19 reviews for Nose-To-Mouth Wrinkle Treatment with UV Chromophores

  1. Margaret B. — February 18, 2026

    Margaret B. –

    Still learning so far I think it is working

  2. Margaret B. — November 27, 2025

    Margaret B. –

    Using and waiting for results

  3. Suzanne — September 18, 2023

    Suzanne –

    Not sure if this helped
    And I expected more for the price.

  4. Lia F. — April 9, 2023

    Lia F. –

    Found this line in Barney’s New York more than 10 years ago. Have loyally used ever since. Nothing I have used between has given me the same results. So glad to have discovered bionova

  5. TrudiKnows — March 2, 2023

    TrudiKnows –

    I tried this on one side versus the other to test it out – I really must say it worked. I am now catching up the other side. Got some congestion out the pores first week, nothing terrible. Will continue

  6. L.P. — February 26, 2023

    L.P. –

    Very happy with this product. Tried smile patches this is much more effective. Skin is tighter.

  7. katyyip — February 21, 2023

    katyyip –

    really happy. Wrinkles better. I am smiling. All Good results here!

  8. Linora — February 15, 2023

    Linora –

    I tried this from an ad and the smell surprised me, I am working with it as the results are there and its not too bad. Had worse things and this actually delivers. The little lines on the sides are softer and the bigger smile line is getting flatter I think. Either way will continue. It did give me a bit of pimples the first week or more but on the small instructions if your patient and read it did mention this so I was ok and it stopped. I have oiler skin.

  9. gigigal — February 7, 2023

    gigigal –

    I got this in a gift bag and tried it, got the full size and happy ..the pouches on the side of my face are really suprisingly tighter and smoother.

  10. carol — February 4, 2023

    carol –

    I got this on macys and liked it, trying other products now, I can see what others mean about the smell, I am ok with it.

  11. julia.r — January 25, 2023

    julia.r –

    I been using this brand for years, since Barneys. Very happy always.

  12. justinekari — January 22, 2023

    justinekari –

    had a friend suggest this product. So far so good smell and all.

  13. aritomas — January 15, 2023

    aritomas –

    really could not go with the smell. Didn’t use long enough to get results

  14. lisar. — January 4, 2023

    lisar. –

    I really could not work with the smell part. I hope they can do something as I did see changes in the sides of lower parts of the lines. Need a better smell to continue.

  15. Victoria B. — December 1, 2022

    Victoria B. –

    Cream actually works

  16. Janis — November 9, 2022

    Janis –

    This product is really great.

  17. Andrea D. — November 9, 2021

    Andrea D. –

    I have been using Nose-to-Mouth Wrinkle Treatment for several years now, and it really works! I use it as suggested to prevent lines, but also for some small pouches around frown lines on my chin which really needed attention. Those pouches are almost gone! It takes some weeks, but keep at it and the results are there! Thank you bn science!!

  18. Victoria B. — January 16, 2021

    Victoria B. –

    Excellent results, cream is fantastic!

  19. Rego N. — November 24, 2018

    Rego N. –

    My friend was using this product. She made me try it! My lines were getting deep, and I always worried about the future. I hate to get a look of an old, grouchy lady. I bought the entire BIONOVA line, and the results are amazing! I want to share with everybody. I am not a writer and never place reviews. But this line got me, and I feel like sharing my experience with everyone. **Review from Dermstore.com**

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